Qian Xiao

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Xiao, Qian
Assistant Professor
Health Promotion
Health Studies
Sleep, circadian rhythms, cardiometabolic health, neighborhood environment, health disparities
End Degree:
M.P.H. in Epidemiology, University of Michigan, Ann Arbor, MI, USA 2011 Ph.D. in Biological Sciences, University of California, San Diego, La Jolla, CA, USA 2009
E118 FH
Email: Laboratory:
Sleep Epidemiology and Health Disparities Lab
Lab Website:

Courses Taught

  • HHP:3050: Obesity: Causes, Consequences, Prevention and Treatment
  • HHP:4010: Behavioral and Clinical Health Assessment
  • HHP:4030: Social, Policy and Environmental Determinants
  • ​HHP:6020: Research Methods and Ethics
  • HHP:6500: Seminar in Health Promotion


Educational/Research Interests

My current research focuses on understanding the health consequences of sleep deficiency and circadian dysfunction by integrating factors at the individual, biological, and contextual levels. I have conducted multiple epidemiological investigations on sleep deficiency in relation to obesity, cancer and other chronic conditions. I am currently expanding this line of research by investigating the 24-hour circadian rhythms of physical activity and eating behaviors in relation to metabolic health. In addition, I seek to elucidate the biological mechanisms mediating the adverse health outcomes of sleep deficiency and circadian dysfunction, particularly focusing on human metabolism. Finally, I am keen to study sleep disparities in different racial and ethnic groups and across different socioeconomic strata, and evaluate how sleep disparities may contribute to health inequality.


Full list of published work: www.ncbi.nlm.nih.gov/myncbi/browse/collection/51070894/?sort=date&direction=descending . 

  1. Xiao Q, Keadle SK, Berrigan D, Matthews CE. Neighborhood Socioeconomic Deprivation and Weight Change in a Large U.S. Cohort.Am J Prev Med. 2017 Jun;52(6):e173-e181
  2. Xiao Q, Derkach A, Moore SC, Sampson JN, Matthews CE Habitual Sleep and human plasma metabolomics. Metabolomics. 2017 May; 13: 63
  3. Xiao Q, Arem H, Pfeiffer RM, Matthews CE Pre-diagnosis sleep duration, napping and mortality among colorectal cancer survivors in a large US cohort. Sleep. 2017 Apr;40(4): zsx010
  4. Xiao Q, Berrigan D, Matthews CE. A prospective investigation of neighborhood socioeconomic deprivation and self-rated health in a large US cohort. Health and Place. 2017 Mar 44; 70-76
  5. Xiao Q, Gu F, Caporaso N, Matthews CE.Relationship between sleep characteristics and measures of body size and composition in a nationally-representative sample. BMC Obesity. 2016 Nov 11; 3:48
  6. Xiao Q, Moore SC, Keadle SK, Xiang YB, Zheng W, Peters TM, Leitzmann MF, Ji BT, Sampson JN, Shu XO, Matthews CE Objectively measured physical activity and plasma metabolomics in the Shanghai Physical Activity Study. Int J Epidemiol. 2016 Oct; 45(5):1433-1444
  7.  Gu F, Xiao Q, Chu LW, Yu K, Matthews CE, Caporaso NE, Hsing AW. Sleep duration and cancer in the NIH-AARP diet and health study. PLoS One 2016 Sep 9;11(9):e0161561
  8.  Xiao Q, Moore SC, Keadle SK, Xiang YB, Zheng W, Peters TM, Leitzmann MF, Ji BT, Sampson JN, Shu XO, Matthews CE Objectively measured physical activity and plasma metabolomics in the Shanghai Physical Activity Study. Int J Epidemiol. 2016 Apr [Epub ahead of print]
  9.  Drahos J, Xiao Q, Risch HA, Freedman ND, Abnet CC, Anderson LA, Bernstein L, Brown LM, Chow WH, Gammon MD, Kamangar F, Liao LM, Murray LJ, Ward MH, Ye W, Wu AH, Vaughan TL, Whiteman DC, Cook MB. Age-specific risk factor profiles of adenocarcinomas of the esophagus: a pooled analysis from the international BEACON consortium. Int J Cancer. 2016 Jan; 138(1):55-64
  10.  Xiao Q, Signorello LB, Brinton LA, Cohen SS, Blot WJ, Matthews CE. Sleep duration and breast cancer risk among black and white women. Sleep Med. 2015 Dec; [Epub ahead of print]
  11.  Keadle SK, Moore SC, Sampson JN, Xiao Q, Albanes D, Matthews CE. Causes of death associated with prolonged television viewing: NIH-AARP Diet and Health Study. Am J Prev Med. 2015 Dec;49(6):811-21
  12.  Matthews CE, Moore SC, Sampson J, Blair A, Xiao Q, Keadle SK, Hollenbeck A, Park Y. Mortality Benefits for Replacing Sitting Time With Different Physical Activities. Med Sci Sports Exerc. 2015 Sept; 47(9):1833-40
  13.  Xiao Q, Brinton LA, Schairer C, Matthews CE. Sleep duration and breast cancer risk in the Breast Cancer Detection Demonstration Project. Br J Cancer. 2015 Feb; 112(3):567-71
  14. Xiao Q, Sinha R, Graubard BI, Freedman ND. Inverse associations of total and decaffeinated coffee with liver enzyme levels in National Health and Nutrition Examination Survey 1999-2010. Hepatology. 2014 Dec; 60(6): 2091-8
  15.  Xiao Q, Keadle SK, Hollenbeck AR, Matthews CE Sleep duration and total and cause-specific mortality in a large US cohort: interrelationships with physical activity, sedentary behavior, and body mass index. Am J Epidemiol.2014 Nov; 180(10):997-1006
  16.  Xiao Q, Liao L, Matthews CE, Chow WH, Davis F, Schwartz K, Purdue M, Hofmann JN, Colt J Physical activity and renal cell carcinoma among black and white Americans. BMC Cancer. 2014 Sep; 14(1):707
  17.  Guertin KA, Moore SC, Sampson JN, Xiao Q, Stolzenberg-Solomon RZ, Sinha Rashmi, Cross AJ Metabolomics in nutritional epidemiology: identifying metabolites associated with diet and quantifying their potential to uncover diet-disease relations in populations. Am J Clin Nutr. 2014 Jul; 100(1):208-17
  18.  Xiao Q, Moore SC, Boca SM, Matthews CE, Rothman N, Stolzenberg-Solomon RZ, Sinha R, Cross AJ, Sampson JN. Sources of variability in metabolite measurements from urinary samples. PLoS One.2014 May; 9(5):e95749
  19.  Xiao Q, Hsing AW, Park Y, Moore SC, Matthews CE, Berrington de González A, Kitahara CM. Body mass index and mortality among blacks and whites in the Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial. Obesity (Silver Spring). 2014 Jan; 22(1)260-8
  20. Xiao Q, Arem H, Moore SC, Hollenbeck A, Matthews CE. A large prospective investigation of sleep duration, weight change and obesity in the NIH-AARP Diet and Health Study Cohort. Am J Epidemiol. 2013 Dec; 178(11):1600-10
  21.  Xiao Q, Yang HP, Wentzensen N, Hollenbeck A, Matthews CE. Physical activity in different periods of life, sedentary behavior and the risk of ovarian cancer in the NIH-AARP Diet and Health Study. Cancer Epidemiol Biomarkers Prev. 2013 Nov; 22(11):2000-8
  22.  Xiao Q, Murphy RA, Houston DK, Harris TB, Chow W, Park Y. Dietary and supplemental calcium intake and cardiovascular disease mortality: the National Institutes of Health-AARP diet and health study. JAMA Intern Med. 2013 Apr; 173(8):639-46

Fellowships and Affiliations

  • American Academy of Sleep Medicine
  • Sleep Research Society
  • Society for Epidemiologic Research